Experts Seek Answers to Race Gap in Prostate Cancer
July 21st, 2009Researchers across the country are working painstakingly to determine why Black men develop prostate cancer at an earlier age and at twice the rate of any other group in America. Experts have long believed that there is a genetic link. For the past dozen years, Georgia Dunston, the founding director of Howard University’s National Human Genome Center, and Chiledum Ahaghotu have led the charge to figure out the racial component of the prostate cancer conundrum. They established the African-American Hereditary Prostate Cancer Study to study the family genes of Black men with prostate cancer. By tracking the health and genetic makeup of different generations, they aim to better understand why prostate cancer is so deadly among Black men and whether the disease is primarily inherited or caused by environmental or lifestyle factors. “We’re looking for those individuals who can give us an indicator of what are the genes that are associated with that underlying cancer,” said Dunston. “Because it’s not a difference in the gene – the difference is whether you’re born with it or it’s caused by changes that develop later in life.” More than a dozen research centers, including D.C.’s Howard University, have recruited Black men and their relatives – siblings, fathers, uncles, grandfathers, great-grandfathers from a total of 77 families – and recorded their medical history. With support from the National Institutes of Health and the National Human Genome Research Institute, AAHPC researchers have been sifting through family health records and looking at the participants’ genetic makeup, through blood samples, to see whether there are common genetic mutations or markers that are linked to the disease.
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Mediterranean diet fights heart disease. People who eat a strict Mediterranean diet are less at risk of developing heart disease, cancer, Parkinson’s and Alzheimer’s disease, Italian researchers report. A so-called Mediterranean diet is rich in olive oil, grains, fruits, nuts, vegetables and fish, and includes a moderate amount of red wine, but is low in meat, dairy products and other alcohol. “This study helps us to support all the recommendations and the nutritional guidelines on the benefit of Mediterranean diet on mortality from all the causes, as well as on the incidence of cardiovascular, neoplastic and degenerative diseases,” lead researcher Dr. Francesco Sofi, from the Department of Medical and Surgical Critical Area at the Thrombosis Centre at the University of Florence, told HealthDay. “By improving the food quality of the population, we would likely reduce the incidence of these diseases by nearly 10 percent,” Sofi added. The analysis of information on more than 1.5 million people showed that people who strictly followed Mediterranean diets had significant improvements in health. They saw an overall drop in deaths of 9 percent, a 9-percent drop in death from cardiovascular disease, a 13-percent reduction in cases of Parkinson’s and Alzheimer’s disease, and a 6-percent drop in cancer. The report was published in the Sept. 11 online edition of the British Medical Journal. 
